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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REV3L All Species: 10.3
Human Site: S532 Identified Species: 28.33
UniProt: O60673 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60673 NP_002903.3 3130 352776 S532 D G T A D E N S D N P L N N E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086055 3130 352672 S532 D G T A D E N S D N P L N N E
Dog Lupus familis XP_539084 3058 344677 T488 I F H K D A A T L E P P S S A
Cat Felis silvestris
Mouse Mus musculus Q61493 3122 350641 N531 L D G T A D E N S D N P L N N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520025 1544 171107
Chicken Gallus gallus XP_426179 3135 353106 D521 G T A D E N G D N P L N N E S
Frog Xenopus laevis NP_001163919 3139 352589 S528 D G T A D E N S D N P L N K E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786092 3425 381348 W564 L R P G A L N W L L K M F N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14284 1504 172939
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.4 90 N.A. 86.5 N.A. N.A. 35.1 72.3 58.1 N.A. N.A. N.A. N.A. N.A. 31.5
Protein Similarity: 100 N.A. 97.9 92.9 N.A. 91.8 N.A. N.A. 41.4 82.8 72.4 N.A. N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 N.A. 100 13.3 N.A. 6.6 N.A. N.A. 0 6.6 93.3 N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 N.A. 100 33.3 N.A. 26.6 N.A. N.A. 0 20 93.3 N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 34 23 12 12 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 12 0 12 45 12 0 12 34 12 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 34 12 0 0 12 0 0 0 12 45 % E
% Phe: 0 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % F
% Gly: 12 34 12 12 0 0 12 0 0 0 0 0 0 0 0 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 12 0 0 12 0 % K
% Leu: 23 0 0 0 0 12 0 0 23 12 12 34 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 12 45 12 12 34 12 12 45 45 12 % N
% Pro: 0 0 12 0 0 0 0 0 0 12 45 23 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 34 12 0 0 0 12 12 12 % S
% Thr: 0 12 34 12 0 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _